Discover the Impact of HSX Data on Healthcare Research

HealthShare Exchange (HSX) advances healthcare research by providing a rich, real-time clinical data repository. Aggregating diverse data from multiple sources, HSX enables in-depth studies on healthcare outcomes, offering insights that improve patient care, optimize delivery, and drive public health advancements. Researchers can uncover trends around outcomes and health disparities and develop evidence-based interventions to enhance health outcomes.

Empowering Breakthrough Research with Comprehensive Regional Healthcare Data

HSX offers researchers affordable access to a comprehensive clinical data repository, encompassing information from over 630 healthcare organizations and more than 12 million patients, with records dating back to 2017. This secondary data is up-to-date, unbiased, and sourced from a trusted platform, providing invaluable support for research initiatives and strengthening funding applications.

Key Benefits:

  1. Broad, Real-World Insights: Comprehensive, cross-setting data reduces reliance on self-reported information and fills gaps across siloed systems.
  2. Longitudinal Tracking: Longitudinal data since 2017 enable impactful studies on chronic diseases, interventions, and health trends.
  3. Health for All: The dataset spans the greater Philadelphia region and supports the analysis of trends in healthcare delivery.
  4. Compliance & Support: HIPAA/IRB-compliant data with added services like consultation and cleaning.
What kinds of data are available?

Our clinical data repository (CDR) is a comprehensive database that stores a wide variety of patient-related information. Our repository is compliant with all relevant privacy regulations, including HIPAA. Access to specific datasets is governed by IRB approval, HSX’s research-related use cases, and data-use agreements. De-identified data can be provided for exploratory analysis, while identifiable data is accessible under certain conditions and only by HSX members.

Examples of Past Research Projects

HealthShare Exchange (HSX) has been a trusted resource for researchers seeking to unlock insights into healthcare outcomes. Here are just a few examples of how our data set has been used:

  • Applied health services and impact analysis:

Enhancing healthy reintegration and recovery for high-risk opioid users

Principal Investigator, Steven Belenko, Ph.D.

Temple University

This project examines ways to improve access to medication-assisted treatment (MAT) for formerly incarcerated individuals with opioid use disorder (OUD) in Philadelphia. It tracks outcomes for those who started MAT while incarcerated and implements an intervention through the TRUST Clinic at Temple Hospital using the hub-and-spoke model. Goals include reducing relapse, overdose, and reincarceration while increasing treatment engagement. The study also identifies health system barriers to MAT and supports minority student training in addiction, criminal justice, and public health through Lincoln University.

  • Translational clinical research:

Sequential modeling for prediction of periodontal diseases

Principal Investigator, Marisol Tellez Merchan, Ph.D.

Temple University’s Kornberg School of Dentistry

This project aims to enhance research and training in periodontal disease. The project aims to validate the Subgingival Oral Microbiome Dysbiosis Index (SMDI)/Saliva Microbial Dysbiosis Index (SaMDI) as predictors of periodontal disease (PD) incidence and progression, and 2) to identify potential high-resolution microbial biomarkers of PD progression. Developing AI-driven tools to predict PD incidence and progression using data from electronic health records and microbiome/metagenomic analyses.

  • Population health research:

Do indicators of social determinants of health improve the prediction of COVID-19 outcomes in a diverse cohort of patients?

Principal Investigator, Pricilia Mullachery, Ph.D., MPH

Drexel University

This Robert Wood Johnson Foundation-funded project investigates COVID-19 inequities using patient-level electronic health records from HealthShare Exchange (HSX) linked with neighborhood-level socioeconomic and built environment data. The study aims to enhance prediction models for COVID-19 hospitalization and deaths by incorporating social determinants of health (SDOH) and identifying high-risk communities, particularly among poor and racial minority groups. Findings will inform policies to mitigate risks and improve health outcomes.

Getting Started with HSX

Explore current use cases for secondary use of HSX data here: https://healthshareexchange.org/hsx-approved-policies/

Contact HSX to discuss your research goals and data needs by emailing Dolores Espinal at dolores.espinal@healthshareexchange.org.

 

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